Molecular alterations in gastric preneoplastic lesions and early gastric cancer

S Battista, MR Ambrosio, F Limarzi, G Gallo… - … journal of molecular …, 2021 - mdpi.com
… mutations in the tumor suppressor gene CDH1, although … in preneoplastic and neoplastic
lesions of the stomach, with … parameters, microsatellite status, and frequency of TP53 mutations …

Targeted genetic and epigenetic profiling of esophageal adenocarcinomas and non-dysplastic Barrett's esophagus

R Pinto, T Hauge, M Jeanmougin, HD Pharo… - Clinical …, 2022 - Springer
… of selected genetic (TP53 mutations and microsatellite … the lower esophagus is replaced by
specialized columnar intestinal … As for other solid cancer types, the TP53 tumor suppressor is …

The mismatch repair system (MMR) in head and neck carcinogenesis and its role in modulating the response to immunotherapy: a critical review

M Cilona, LG Locatello, L Novelli, O Gallo - Cancers, 2020 - mdpi.com
… of specific genetic sequences, known as microsatellites, and … such as colon, stomach, prostate,
esophagus, endometrium, … of oncogenes/tumor suppressor genes such as p16 and p53. …

Molecular landscapes of gastric pre-neoplastic and pre-invasive lesions

G Businello, V Angerilli, P Parente, S Realdon… - … Journal of Molecular …, 2021 - mdpi.com
microsatellite unstable (MSI) tumors (23%), (ii) microsatellite … reported to act as a tumor
suppressor and to be dysregulated … are benign neoplasms of the upper third of the stomach

Small bowel epithelial precursor lesions: a focus on molecular alterations

A Vanoli, F Grillo, D Furlan, G Arpa, O Grami… - … Journal of Molecular …, 2021 - mdpi.com
Microsatellite instability has been reported to be absent or … as well as those of the stomach.
Mutations in other oncogenes… in APC, a tumor suppressor gene which plays a pivotal role in …

[HTML][HTML] Molecular genetic changes in gastric carcinoma

J Singh, P Kumar, K Verma, SK Tiwary… - … Journal of Molecular …, 2021 - ijmio.com
tumor suppressor genes, oncogenes, cellcycle regulators, apoptosis, cell-adhesion molecules,
loss of heterozygosity, microsatellite … because the stomach intramucosal unlike the colon

Cancer and genomic instability

I Kovalchuk - Genome stability, 2021 - Elsevier
… or contraction of repeated microsatellite sequences and clonal … in oncogenes and tumor
suppressor genes which play an … , stomach and colon adenocarcinomas showed that a …

Early Gastric Cancer: Identification of molecular markers able to distinguish submucosa-penetrating lesions with different prognosis

C Molinari, G Tedaldi, F Rebuzzi, P Morgagni, L Capelli… - Gastric Cancer, 2021 - Springer
… fragment analysis of two microsatellites closed to TP53 locus… , despite their tumor suppressor
role in the intestinal tract, … of distinguishing early-stage stomach tumors, Pen A and Pen B. …

From genetics to histomolecular characterization: an insight into colorectal carcinogenesis in Lynch syndrome

M Lepore Signorile, V Disciglio, G Di Carlo… - … Journal of Molecular …, 2021 - mdpi.com
… extra-colonic malignancies, such as stomach, small bowel, … non-coding microsatellite
regions (microsatellite instability; … upon mutations in major tumor suppressor genes, such as …

Multifaceted roles of DNA methylation in neoplastic transformation, from tumor suppressors to EMT and metastasis

L Casalino, P Verde - Genes, 2020 - mdpi.com
… and silencing of tumor suppressor genes (TSG) [7]. … Reactivation of centromeric satellite
repeats (microsatellites) and … is also detectable in esophageal, gastric, colon, and renal cancer in …